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HarvardScience is a publication of the Harvard Office of News and Public Affairs devoted to all matters related to science at the various schools, departments, institutes, and hospitals of Harvard University.
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Prehistoric quid (wads of crumpled, masticated, shredded leaves) from dry caves in the American Southwest.

Photo by Steven LeBlanc

Scientists have something to chew on

Ancient yucca chaws yield ancient DNA

August 31, 2007

In a groundbreaking study, two Harvard scientists have for the first time extracted human DNA from ancient artifacts. The work potentially opens up a new universe of sources for ancient genetic material, which is used to map human migrations in prehistoric times.

Before this, archaeologists could only get ancient DNA from relics of the human body itself, including prehistoric teeth, bones, fossilized feces, or — rarely — preserved flesh. Such sources of DNA are hard to find, poorly preserved, or unavailable because of cultural and legal barriers.

By contrast, the genetic material used in the Harvard study came from two types of artifacts — 800 to 2,400 years old — that are found by the hundreds at archaeological sites in the American Southwest.

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