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HarvardScience is a publication of the Harvard Office of News and Public Affairs devoted to all matters related to science at the various schools, departments, institutes, and hospitals of Harvard University.
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In a recent JAMA, Barry Bloom and colleagues describe the most promising approaches to developing vaccines against HIV, TB, and the malaria parasite, the leading causes of death and disability in the world among infectious and parasitic diseases.

Photo by Steve Gilbert

New vaccines could balance global burden of disease

Programs often depend as much on political will as scientific capability

February 23, 2001

The scientific community believes that diseases that have long plagued the world can be controlled by vaccination. But vaccines won't work unless they reach the people who need them most -- and that means mostly people in poor countries. In two articles in the Journal of the American Medical Association, Harvard School of Public Health Dean Barry Bloom addresses this problem. Bloom and his colleagues describe the most promising approaches to vaccine development and encourage an international effort for testing and distribution. "AIDS, TB, and malaria are more severe problems in poor countries than in affluent ones, and these diseases have not received an investment in research dollars commensurate with their importance," write Bloom and colleagues Norman Letvin and Stephen Hoffman.

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