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Jordan W. Smoller found a link between panic attacks and heart attacks in older women. Here, Smoller performs a blood pressure test.

Staff photo Kris Snibbe/Harvard News Office

Research links panic and heart attack in older women

Heart attack risk rises four times for panic victims

October 1, 2007

By Alvin Powell

New research has linked panic attacks in older women with an increased risk of heart attack, stroke, and death from all causes, adding panic attacks to the growing list of mental and emotional conditions with potentially deadly physical effects.

A study of more than 3,300 women ages 51 to 83 indicated that panic attacks were relatively common, suffered by about 10 percent of those in the study. While heart attacks and strokes were relatively rare, those suffering panic attacks had four times the risk of heart attack, three times the risk of heart attack or stroke, and twice the risk of dying from any cause as those who didn’t.

“This adds panic attacks to the growing body of evidence that emotional states and psychological symptoms are relevant to physical outcomes,” said Jordan Smoller, associate professor of psychiatry at Harvard Medical School and Massachusetts General Hospital (MGH), associate professor of epidemiology at the Harvard School of Public Health, and the study’s lead author.

Smoller said the link between panic attack and health remains unclear. The study controlled for 14 known variables, including age, race, income, body mass index, alcohol consumption, smoking, hormone use, high cholesterol or blood pressure, level of physical activity, atrial fibrillation, depression, and history of diabetes or cardiovascular disease.

A panic attack’s influence on health appears to be independent of any of those factors, Smoller said. That doesn’t rule out, however, some other unknown underlying condition at work, causing both panic attacks and increased health risks.

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