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HarvardScience is a publication of the Harvard Office of News and Public Affairs devoted to all matters related to science at the various schools, departments, institutes, and hospitals of Harvard University.
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Marilyn Albert leads a research team that has linked shrinkage in various parts of the brain, a split model of which she holds, to early stages of Alzheimer's disease.

Staff photo by Kris Snibbe

Scans predict Alzheimer's risk

Tests differentiate memory lapses from onset of disease

April 27, 2000

At present, physicians live with the frustration of not being able to provide much help to people diagnosed with Alzheimer's. Things should change dramatically if the disease, like cancer, can be identified in its earliest stages and treatments begun as soon as possible. Researchers recently have identified telltale brain shrinkage that presages Alzheimer's. Using brain scanning techniques, they distinguished between people considered normal and those with memory problems that progressed to Alzheimer's with 93 percent accuracy. The same brain scans that find the disease could also be used to determine the efficacy of treatments to control it. For example, does a particular drug lessen, or even prevent, brain shrinkage?

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