http://harvardscience.harvard.edu/stories/person/1910 Stories and external links referencing a person (RSS) en http://harvardscience.harvard.edu/medicine-health/articles/evolution-follows-few-possible-paths-antibiotic-resistance <!--paging_filter--><p>Darwinian evolution follows very few of the available mutational pathways to attain fitter proteins, researchers at Harvard University have found in a study of a gene whose mutant form increases bacterial resistance to a widely prescribed antibiotic by a factor of roughly 100,000. Their work indicates that of 120 harrowing, five-step mutational paths that theoretically could grant antibiotic resistance, only about 10 actually endow bacteria with a meaningful evolutionary advantage.</p> <p>The research is described this week in the journal Science.</p> <p><a href="http://harvardscience.harvard.edu/medicine-health/articles/evolution-follows-few-possible-paths-antibiotic-resistance">read more</a></p> Wed, 18 Jul 2007 12:33:28 -0400 50443248 4424 at http://harvardscience.harvard.edu