http://harvardscience.harvard.edu/topic/20008 Stories within a topic (RSS) en http://harvardscience.harvard.edu/medicine-health/articles/researchers-identify-promising-cancer-drug-target-prostate-tumors <!--paging_filter--><p>Scientists at <a title="" href="http://www.dana-farber.org/">Dana-Farber Cancer Institute</a> report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a "powerhouse" that drives runaway cell growth.</p><p>In a letter appearing in an advanced online <a title="" href="http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature07091.html">publication</a> by the journal Nature, the researchers said the growth-stimulating molecule called p110beta — part of a cellular signaling network disrupted in several common cancers — is a promising target for novel cancer therapies designed to shut it down. The report's lead authors are Shidong Jia, Zhenning Liu, Sen Zhang, and Pixu Liu.</p><p><a href="http://harvardscience.harvard.edu/medicine-health/articles/researchers-identify-promising-cancer-drug-target-prostate-tumors">read more</a></p> Tue, 01 Jul 2008 15:26:05 -0400 404132862 20301 at http://harvardscience.harvard.edu http://harvardscience.harvard.edu/medicine-health/articles/prostate-cancer-treatments-often-not-matched-patient-needs <!--paging_filter--><p>More than a third of men with early <a title="" href="http://www.cancer.gov/cancertopics/types/prostate">prostate cancer</a> who participated in a study analyzing treatment choice received therapies that might not be appropriate, based on pre-existing problems with urinary, bowel or sexual function. </p><p><a href="http://harvardscience.harvard.edu/medicine-health/articles/prostate-cancer-treatments-often-not-matched-patient-needs">read more</a></p> Mon, 26 Nov 2007 15:54:30 -0500 404132862 20006 at http://harvardscience.harvard.edu